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Table 3 Distribution of the 30 analysed long-term conditions across defined clusters

From: Patient-oriented unsupervised learning to uncover the patterns of multimorbidity associated with stroke using primary care electronic health records

Cluster #

1

2

3

4

5

6

7

8

Total

P

Coronary Heart Disease

419 (17.5)

335 (18.5)

382 (21.4)

267 (18.9)

84 (9.9)

140 (20.4)

10 (1.8)

19 (5.3)

1656 (16.8)

<0.001

Parkinson’s disease

61 (2.6)

58 (3.2)

39 (2.2)

16 (1.1)

5 (0.6)

17 (2.5)

0 (0.0)

2 (0.6)

198 (2.0)

<0.001

Heart Failure

296 (12.4)

264 (14.6)

278 (15.6)

190 (13.5)

63 (7.5)

113 (16.5)

12 (2.1)

7 (2.0)

1223 (12.4)

<0.001

Osteoarthritis

566 (23.7)

401 (22.1)

421 (23.6)

324 (23.0)

138 (16.3)

683 (99.7)

26 (4.6)

24 (6.7)

2583 (26.2)

<0.001

Asthma

441 (18.4)

244 (13.5)

79 (4.4)

72 (5.1)

342 (40.5)

38 (5.5)

27 (4.8)

12 (3.4)

1255 (12.7)

<0.001

Serious Mental Illness

280 (11.7)

50 (2.8)

26 (1.5)

32 (2.3)

46 (5.4)

2 (0.3)

16 (2.8)

7 (2.0)

459 (4.7)

<0.001

Hypertension

1430 (59.8)

1206 (66.5)

1424 (79.9)

1301 (92.3)

352 (41.7)

485 (70.8)

64 (11.4)

82 (23.0)

6344 (64.4)

<0.001

Depression

844 (35.3)

317 (17.5)

200 (11.2)

274 (19.4)

531 (62.8)

84 (12.3)

64 (11.4)

26 (7.3)

2340 (23.8)

<0.001

Anxiety Disorders

517 (21.6)

329 (18.1)

146 (8.2)

233 (16.5)

570 (67.5)

91 (13.3)

79 (14.0)

23 (6.4)

1988 (20.2)

<0.001

Cancer

460 (19.2)

387 (21.3)

351 (19.7)

133 (9.4)

85 (10.1)

88 (12.8)

9 (1.6)

25 (7.0)

1538 (15.6)

<0.001

Peripheral Aterial/Vascular Disease

169 (7.1)

111 (6.1)

181 (10.2)

113 (8.0)

25 (3.0)

52 (7.6)

1 (0.2)

1 (0.3)

653 (6.6)

<0.001

Diabetes

626 (26.2)

409 (22.5)

710 (39.8)

831 (59.0)

177 (20.9)

190 (27.7)

26 (4.6)

37 (10.4)

3006 (30.5)

<0.001

Chronic Kidney Disease Stage 3-5

444 (18.6)

514 (28.3)

565 (31.7)

423 (30.0)

107 (12.7)

207 (30.2)

22 (3.9)

14 (3.9)

2296 (23.3)

<0.001

Viral Hepatitis (B&C)

105 (4.4)

10 (0.6)

9 (0.5)

21 (1.5)

23 (2.7)

6 (0.9)

6 (1.1)

5 (1.4)

185 (1.9)

<0.001

Inflammatory Bowel Disease

58 (2.4)

23 (1.3)

16 (0.9)

18 (1.3)

19 (2.2)

14 (2.0)

4 (0.7)

1 (0.3)

153 (1.6)

<0.001

Liver Disease

99 (4.1)

17 (0.9)

14 (0.8)

22 (1.6)

37 (4.4)

6 (0.9)

3 (0.5)

1 (0.3)

199 (2.0)

<0.001

Epilepsy

378 (15.8)

58 (3.2)

61 (3.4)

66 (4.7)

71 (8.4)

38 (5.5)

46 (8.2)

14 (3.9)

732 (7.4)

<0.001

Osteopotosis

94 (3.9)

206 (11.4)

118 (6.6)

29 (2.1)

23 (2.7)

67 (9.8)

2 (0.4)

5 (1.4)

544 (5.5)

<0.001

Dementia/Alzheimer’s

277 (11.6)

460 (25.4)

352 (19.8)

132 (9.4)

42 (5.0)

172 (25.1)

4 (0.7)

12 (3.4)

1451 (14.7)

<0.001

Sickle Cell Anaemia

11 (0.5)

1 (0.1)

1 (0.1)

3 (0.2)

2 (0.2)

1 (0.1)

41 (7.3)

0 (0.0)

60 (0.6)

<0.001

Multiple Sclerosis

12 (0.5)

0 (0.0)

1 (0.1)

0 (0.0)

7 (0.8)

0 (0.0)

2 (0.4)

0 (0.0)

22 (0.2)

<0.001

HIV/AIDS

85 (3.6)

1 (0.1)

3 (0.2)

10 (0.7)

11 (1.3)

0 (0.0)

2 (0.4)

1 (0.3)

113 (1.1)

<0.001

Myocardial infarction

222 (9.3)

163 (9.0)

238 (13.4)

127 (9.0)

48 (5.7)

66 (9.6)

8 (1.4)

7 (2.0)

879 (8.9)

<0.001

Atrial Fibrillation

365 (15.3)

491 (27.1)

388 (21.8)

141 (10.0)

74 (8.8)

184 (26.9)

13 (2.3)

16 (4.5)

1672 (17.0)

<0.001

Lupus

34 (1.4)

1 (0.1)

4 (0.2)

4 (0.3)

7 (0.8)

1 (0.1)

1 (0.2)

0 (0.0)

52 (0.5)

<0.001

Chronic Obstructive Pulmonary Disease

337 (14.1)

249 (13.7)

152 (8.5)

60 (4.3)

85 (10.1)

54 (7.9)

9 (1.6)

8 (2.2)

954 (9.7)

<0.001

Rheumatoid Arthritis

89 (3.7)

29 (1.6)

19 (1.1)

29 (2.1)

15 (1.8)

21 (3.1)

2 (0.4)

1 (0.3)

205 (2.1)

<0.001

Transient Ischemic Attack

443 (18.5)

283 (15.6)

425 (23.8)

165 (11.7)

109 (12.9)

111 (16.2)

12 (2.1)

9 (2.5)

1557 (15.8)

<0.001

Cognitive and learning disability

49 (2.0)

2 (0.1)

3 (0.2)

9 (0.6)

9 (1.1)

2 (0.3)

11 (2.0)

0 (0.0)

85 (0.9)

<0.001

Total N (%)

2392 (24.3)

1814 (18.4)

1782 (18.1)

1409 (14.3)

845 (8.6)

685 (7.0)

563 (5.7)

357 (3.6)

9847

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